Parkinson's Disease & Movement Disorders Multicenter Database and Collaborative Network in China（PD-MDCNC）v7.0 中国帕金森病及运动障碍疾病多中心数据库及协作网

The PD-MDCNC is devoted to medical genetics and genomic research of neurodegenerative and hereditary diseases. With a large database of whole-exome sequencing (WES) and whole-genome sequencing (WGS) data, the PD-MDCNC provides support for identifying loci and gene variants that increase the disease risk, as well as pathogenic gene variants. Currently, the PD-MDCNC genome database includes WES data of 2,647 patients with Parkinson’s disease (PD), 1,005 patients with amyotrophic lateral sclerosis (ALS), 282 patients with Alzheimer's disease (AD), 1,258 healthy controls, and 150 patients with neurodegenerative and hereditary diseases; WGS data of 3,621 patients with PD, 1,180 with AD, 1,224 with essential tremor, 500 with spinocerebellar ataxia and 4,099 healthy controls; and long read sequence (LRS) data of 287 patients with neurodegenerative and hereditary diseases.